http://universityofhawaii.technologypublisher.comBe the first to know about the latest inventions and technologies available from University of Hawaiien-USThu, 14 May 2026 12:06:19 GMTThu, 24 Oct 2024 08:22:12 GMThttp://blogs.law.harvard.edu/tech/rssdjleong@hawaii.eduCopyright 2026, University of Hawaii25/0011http://universityofhawaii.technologypublisher.com/technology/55458Thu, 24 Oct 2024 08:22:12 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/5545823/0031http://universityofhawaii.technologypublisher.com/technology/50927Fri, 28 Apr 2023 08:17:24 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/5092722/0041http://universityofhawaii.technologypublisher.com/technology/50648Thu, 16 Mar 2023 13:15:52 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/5064820/0031http://universityofhawaii.technologypublisher.com/technology/40189Wed, 10 Jun 2020 15:16:16 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/4018920/0004http://universityofhawaii.technologypublisher.com/technology/35451Tue, 13 Aug 2019 11:37:00 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/3545119/0041http://universityofhawaii.technologypublisher.com/technology/34931Thu, 11 Jul 2019 13:04:45 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/3493119/0027http://universityofhawaii.technologypublisher.com/technology/34373Tue, 21 May 2019 19:51:40 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/3437301120http://universityofhawaii.technologypublisher.com/technology/34372Tue, 21 May 2019 19:48:41 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/3437201028http://universityofhawaii.technologypublisher.com/technology/32472Tue, 23 Apr 2019 16:04:38 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/3247201096http://universityofhawaii.technologypublisher.com/technology/32086Fri, 12 Apr 2019 14:02:04 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/3208618/0006http://universityofhawaii.technologypublisher.com/technology/32005Tue, 09 Apr 2019 18:23:47 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/3200518/0031http://universityofhawaii.technologypublisher.com/technology/31203Thu, 31 Jan 2019 13:05:14 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/3120318/0007http://universityofhawaii.technologypublisher.com/technology/31200Wed, 30 Jan 2019 16:09:49 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/3120001054http://universityofhawaii.technologypublisher.com/technology/30491Fri, 11 Jan 2019 15:48:10 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/3049100539http://universityofhawaii.technologypublisher.com/technology/30380Fri, 21 Dec 2018 13:14:23 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/3038000538http://universityofhawaii.technologypublisher.com/technology/30379Fri, 21 Dec 2018 13:09:57 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/3037901062http://universityofhawaii.technologypublisher.com/technology/28222Fri, 20 Jul 2018 16:38:55 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/2822218/0024http://universityofhawaii.technologypublisher.com/technology/26941Mon, 22 Jan 2018 14:31:53 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/2694101105http://universityofhawaii.technologypublisher.com/technology/26371Despite a notable role for amyloid and amyloid plaques in Alzheimer's disease, treatments aimed at lowering the levels of beta amyloid or disrupting amyloid plaques have had little or no impact on the disease. Using a novel approach, a core hexapeptide fragment derived from beta amyloid has been shown to be protective at the synaptic, cellular and behavioral levels against beta amyloid toxicity and is being used in this invention as a platform for deriving stabilized versions and peptidomimetics for prevention and treatment of Alzheimer's disease. The hexapeptide core beta amyloid fragment is ...Thu, 05 Oct 2017 19:01:38 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/2637118/0003http://universityofhawaii.technologypublisher.com/technology/26370Hydrogen storage is one of the great challenges limiting the commercialization of polymer electrolyte membrane (PEM) fuel cell technology for automobile and unmanned vehicles. Full commercialization is dependent upon the development of compact and cost competitive hydrogen storage technologies with longer drive range and capability of meeting practical performance targets. Researchers at the University of Hawaii have developed novel magnesium boride based materials that undergo rapid, reversible hydrogenation at significantly lower temperatures and pressures than current state-of-the-art pure ...Thu, 05 Oct 2017 17:39:48 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/2637001113http://universityofhawaii.technologypublisher.com/technology/26324Mon, 25 Sep 2017 14:03:07 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/2632401143http://universityofhawaii.technologypublisher.com/technology/26323Mon, 25 Sep 2017 13:27:21 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/2632301112http://universityofhawaii.technologypublisher.com/technology/25773Wed, 26 Jul 2017 10:56:56 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/2577301100http://universityofhawaii.technologypublisher.com/technology/23905Tue, 31 Jan 2017 13:05:50 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/2390501119http://universityofhawaii.technologypublisher.com/technology/23616Tue, 06 Dec 2016 12:28:10 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/2361601116http://universityofhawaii.technologypublisher.com/technology/23534Fri, 18 Nov 2016 16:57:59 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/2353401078http://universityofhawaii.technologypublisher.com/technology/21496Thu, 03 Mar 2016 18:34:02 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/2149600985http://universityofhawaii.technologypublisher.com/technology/19792Tue, 16 Jun 2015 15:44:23 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/1979200849http://universityofhawaii.technologypublisher.com/technology/19647In the US, asbestos causes approximately 2,000 - 3,000 malignant mesothelioma deaths per year, and it contributes to an even larger number of lung carcinomas. The latency from time of exposure to tumor development potentially allows time for intervention to block the mechanism(s) that trigger asbestos-induced carcinogenesis. This invention proposes administering to a patient having mesothelioma an antibody specific for HMGB1 to neutralize activity against HMGB1 and inhibit mesothelioma cell growth. It also propose use of an anti-HMGB1 antibody to prevent, delay or reduce the incidence of malig...Fri, 29 May 2015 17:46:47 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/1964700850http://universityofhawaii.technologypublisher.com/technology/19646Malignant mesothelioma, associated with asbestos or erionite exposure, is an aggressive and lethal cancer of the mesothelium, the protective lining that covers many internal organs, and is most commonly found in the pleura (outer lining of the lungs). The inventors discovered that misregulation of a protein called High Mobility Group Box 1 (HMGB1) is linked to mesothelioma in subjects exposed to asbestos. HMGB1 is a member of the high-mobility group protein super-family that plays important roles in biological processes like transcription, DNA repair, proliferation and inflammation. After asbe...Fri, 29 May 2015 15:43:43 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/1964600547http://universityofhawaii.technologypublisher.com/technology/19638The two monoclonal antibody cell lines secrete different thiamethoxam antibodies. Thiamethoxam is a new class of neo-nicotinoid insecticides that are used to treat sucking and chewing insects such as aphid, whiteflies, leadhoppers and some beetles. This class of insecticides is one of the most widely used to protect crops and environmental contamination is a possibility. To protect the consumer, a sensitive specific screening assay was needed. The antibodies can determine thiamethoxam at concentrations below 100 ppb. Immunassay companies such as EnviroLogix will use this antibody to develop an...Thu, 28 May 2015 17:00:37 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/1963800903http://universityofhawaii.technologypublisher.com/technology/19637Thu, 28 May 2015 14:26:52 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/1963700950http://universityofhawaii.technologypublisher.com/technology/19629Wed, 27 May 2015 17:07:04 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/1962901035http://universityofhawaii.technologypublisher.com/technology/19597Tue, 26 May 2015 12:21:58 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/1959700663http://universityofhawaii.technologypublisher.com/technology/19513The use of molecular biology techniques to produce pathogen resistant strains of shrimp through genetic transformation technology is considered a highly promising strategy for control of shrimp viral diseases. A major challenge to current development of such technology is the lack of a suitable host-derived promoter to drive the effective expression of desirable genes in shrimp. To meet this urgent need for the development of transgenic shrimp, we have recently employed molecular cloning and sequencing techniques and isolated and identified a putative promoter gene from litopenaeus shrimp (L. ...Thu, 21 May 2015 12:55:22 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/1951300932http://universityofhawaii.technologypublisher.com/technology/12288Wed, 10 Apr 2013 19:38:39 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/1228800934http://universityofhawaii.technologypublisher.com/technology/12287Wed, 10 Apr 2013 18:40:16 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/1228700937http://universityofhawaii.technologypublisher.com/technology/12286Researchers have discovered a new chemical compound that blocks the cancer causing biological molecule called Stat3, and by doing so controls growth and existence of human cancer cells. The compound strongly inhibits the activated form of Stat3, and consequently attenuates Stat3 functions in cancer cells. Accordingly, treatment of human breast cancer and glioma cells in culture leads to inhibition of cell growth and survival, and the ability of the tumor cells to migrate. Altogether, the studies provide data to support the compound as a potential new drug to treat human cancers that show evide...Wed, 10 Apr 2013 16:31:48 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/1228600660http://universityofhawaii.technologypublisher.com/technology/6349Tue, 25 Jan 2011 12:19:15 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/634900130http://universityofhawaii.technologypublisher.com/technology/4739Mon, 15 Mar 2010 19:04:12 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/473900493http://universityofhawaii.technologypublisher.com/technology/4734Fri, 12 Mar 2010 16:45:17 GMTdjleong@hawaii.eduhttp://universityofhawaii.technologypublisher.com/technology/4734