Latest technologies from University of Hawaiihttp://universityofhawaii.technologypublisher.comBe the first to know about the latest inventions and technologies available from University of Hawaiien-USFri, 20 Oct 2017 18:00:42 GMTThu, 05 Oct 2017 19:01:38 GMT 2017, University of HawaiiApplication of Neuroprotective Beta Amyloid Core Peptides and Peptidomimetic Derivatives to the Treatment of Alzheimer's Disease a notable role for amyloid and amyloid plaques in Alzheimer's disease, treatments aimed at lowering the levels of beta amyloid or disrupting amyloid plaques have had little or no impact on the disease. Using a novel approach, a core hexapeptide fragment derived from beta amyloid has been shown to be protective at the synaptic, cellular and behavioral levels against beta amyloid toxicity and is being used in this invention as a platform for deriving stabilized versions and peptidomimetics for prevention and treatment of Alzheimer's disease. The hexapeptide core beta amyloid fragment is ...Thu, 05 Oct 2017 19:01:38 GMTdjleong@hawaii.edu Magnesium Boride Materials for Hydrogen Storage storage is one of the great challenges limiting the commercialization of polymer electrolyte membrane (PEM) fuel cell technology for automobile and unmanned vehicles. Full commercialization is dependent upon the development of compact and cost competitive hydrogen storage technologies with longer drive range and capability of meeting practical performance targets. Researchers at the University of Hawaii have developed novel magnesium boride based materials that undergo rapid, reversible hydrogenation at significantly lower temperatures and pressures than current state-of-the-art pure ...Thu, 05 Oct 2017 17:39:48 GMTdjleong@hawaii.edu Harvesting Technology invention involves a new energy harvesting technology that uses a simple, position-dependent passive switch to harvest the peak electric potential energy generated in the electrostatic induction process as a droplet of liquid moves over different materials. This new technology is perfectly suited to scavenge low-level, otherwise wasted, ambient energy and works over a broad spectrum of vibrational frequencies. The energy created by this technology is directly stored as potential energy and produces a DC current. It requires no additional control circuitry that would reduce it's efficiency...Mon, 25 Sep 2017 14:03:07 GMTdjleong@hawaii.edu Actuator for Medical Device Locating and Positioning, 25 Sep 2017 13:27:21 GMTdjleong@hawaii.edu Expressing the Miraculin Protein, a Sweetener, 26 Jul 2017 10:56:56 GMTdjleong@hawaii.edu Zika Virus from Other Flaviviruses Via Simple Serodiagnostic Assays, 20 Jul 2017 14:14:07 GMTdjleong@hawaii.edu Inhibitors of GSK3-beta, 31 Jan 2017 13:05:50 GMTdjleong@hawaii.edu Voltage Regulators, 22 Dec 2016 09:48:33 GMTdjleong@hawaii.edu'Alawa: A Unique Mechanistic Model for Battery Diagnosis and Prognosis, 06 Dec 2016 12:28:10 GMTdjleong@hawaii.edu Evolved Crop Protection and Insect Control, 18 Nov 2016 16:57:59 GMTdjleong@hawaii.edu Stable Recombinant Peroxidase for Industrial Applications, 21 Oct 2016 17:18:57 GMTdjleong@hawaii.edu Axisymmetric Drop Shape Analysis for Droplet Manipulation at the University of Hawaii have developed a novel method for closed-loop axisymmetric drop shape analysis (CL-ADSA), taking it beyond traditional surface tension measurement to a sophisticated tool for manipulating millimeter-sized droplets. This closed-loop system enables real-time measurement AND precise control of droplet properties such as volume, surface area and surface tension. The feedback control system continuously calculates changes in droplet parameters and automatically drives corrective action to maintain desired droplet characteristics. Inventors have demonstrated the...Thu, 18 Aug 2016 18:00:52 GMTdjleong@hawaii.edu for prevention and treatment of Alzheimer's disease, 13 May 2016 18:59:03 GMTdjleong@hawaii.edu<![CDATA[Apparatus & Method for Estimating the State of Health of a Battery via updating the OCV and SOC relationship]]>, 03 Mar 2016 18:34:02 GMTdjleong@hawaii.edu Real-Time Isothermal Sequence Specific Detection of DNA with Non-Contact Temperature Controller (Exclusively Licensed - please inquire to learn more), rapid, and specific DNA-based diagnostics tools are urgently needed for variety of clinical health application and critical pathogens detection programs for containment, treatment, and eradication. Unfortunately, most instruments for DNA analysis are bulky, slow, require trained operators applying a sequence of operations for sample preparation, and are confined to laboratories isolated from points where they are most immediately needed. With emerging risks such as bio-terrorism, disease pandemics in low resource settings such as the developing world, and devastating accidental introdu...Fri, 12 Feb 2016 16:16:38 GMTdjleong@hawaii.edu Method and Device for Biochemical Sensing (Exclusively Licensed - please inquire for further details) diagnostics using chemical sensing of antibody, antigens, DNA fragments and other biochemicals are addressed using semiconductor sensors and supportive biochemical processes. This successful marriage of semiconductor sensors and biochemistry address a diversity of potential biochemical diagnostics and measurements including detection and quantification of human, animal and plant diseases. Target biochemical molecules attach specifically to one or more preselected, sensor-attached biochemical receptors resulting in a concentration- related, large output electronic output signal...Thu, 11 Feb 2016 17:55:32 GMTdjleong@hawaii.edu for Reducing or Preventing Immunogenic Response, 16 Jun 2015 15:44:23 GMTdjleong@hawaii.edu antibody for mesothelioma the US, asbestos causes approximately 2,000 - 3,000 malignant mesothelioma deaths per year, and it contributes to an even larger number of lung carcinomas. The latency from time of exposure to tumor development potentially allows time for intervention to block the mechanism(s) that trigger asbestos-induced carcinogenesis. This invention proposes administering to a patient having mesothelioma an antibody specific for HMGB1 to neutralize activity against HMGB1 and inhibit mesothelioma cell growth. It also propose use of an anti-HMGB1 antibody to prevent, delay or reduce the incidence of malig...Fri, 29 May 2015 17:46:47 GMTdjleong@hawaii.edu Mesothelioma Biomarker mesothelioma, which is associated with asbestos or erionite exposure, is an aggressive and lethal cancer of the mesothelium, the protective lining that covers many internal organs and is most commonly found in the lungs. The inventors have discovered that misregulation of a protein called High Mobility Group Box 1 (HMGB1) is linked to mesothelioma in individuals exposed to asbestos. HMGB1 is a member of the high-mobility group protein super-family that plays important roles in biological processes like transcription, DNA repair, proliferation and inflammation. After asbestos and erio...Fri, 29 May 2015 15:43:43 GMTdjleong@hawaii.edu antibody cell lines for the insecticide "Thiamethoxam" two monoclonal antibody cell lines secrete different thiamethoxam antibodies. Thiamethoxam is a new class of neo-nicotinoid insecticides that are used to treat sucking and chewing insects such as aphid, whiteflies, leadhoppers and some beetles. This class of insecticides is one of the most widely used to protect crops and environmental contamination is a possibility. To protect the consumer, a sensitive specific screening assay was needed. The antibodies can determine thiamethoxam at concentrations below 100 ppb. Immunassay companies such as EnviroLogix will use this antibody to develop an...Thu, 28 May 2015 17:00:37 GMTdjleong@hawaii.edu method for transforming algae, 28 May 2015 14:26:52 GMTdjleong@hawaii.edu product Stat3 Inhibitors, 27 May 2015 17:07:04 GMTdjleong@hawaii.edu AMPlification (LAMP) Primers that Specifically Detect Clavibacter michiganensis subsp. nebraskensis, 27 May 2015 14:42:46 GMTdjleong@hawaii.edu of lincRNAs as Robust Pan-Cancer Diagnostic and Prognostic Biomarkers, 26 May 2015 13:22:38 GMTdjleong@hawaii.edu product inhibitors of Stat3 and NF-kappaB, 26 May 2015 12:21:58 GMTdjleong@hawaii.edu Sequence of Shrimp Actin Promoter and Its Use in Genetic Transformation Biotechnology use of molecular biology techniques to produce pathogen resistant strains of shrimp through genetic transformation technology is considered a highly promising strategy for control of shrimp viral diseases. A major challenge to current development of such technology is the lack of a suitable host-derived promoter to drive the effective expression of desirable genes in shrimp. To meet this urgent need for the development of transgenic shrimp, we have recently employed molecular cloning and sequencing techniques and isolated and identified a putative promoter gene from litopenaeus shrimp (L. ...Thu, 21 May 2015 12:55:22 GMTdjleong@hawaii.edu for localization of atypical sequences in big data, 10 Apr 2013 19:38:39 GMTdjleong@hawaii.edu chaos computing with adjustable noise immunity level, 10 Apr 2013 18:40:16 GMTdjleong@hawaii.edu novel Stat3 inhibitor that suppresses growth, viability, survival and migration of human breast and glioma cells in vitro have discovered a new chemical compound that blocks the cancer causing biological molecule called Stat3, and by doing so controls growth and existence of human cancer cells. The compound strongly inhibits the activated form of Stat3, and consequently attenuates Stat3 functions in cancer cells. Accordingly, treatment of human breast cancer and glioma cells in culture leads to inhibition of cell growth and survival, and the ability of the tumor cells to migrate. Altogether, the studies provide data to support the compound as a potential new drug to treat human cancers that show evide...Wed, 10 Apr 2013 16:31:48 GMTdjleong@hawaii.edu combined instrument for Raman and LIBS (Laser-induced breakdown) spectrometry, utilizing a single laser source and single spectrograph, 25 Jan 2011 12:19:15 GMTdjleong@hawaii.edu for Direct Transesterification of Microalgal, Yeast, or Oil Seeds in Ionic Liquids, 10 May 2010 12:59:48 GMTdjleong@hawaii.edu Homogeneous Antibody-based FRET Immunoassays, 28 Apr 2010 18:02:05 GMTdjleong@hawaii.edu Digital Surfaced Grid of High Resolution Bathymetry (Including SeaBeam multibeam) and Topography around the Island of Hawaii, 15 Mar 2010 19:04:12 GMTdjleong@hawaii.edu - The Most Cost-Effective Advanced Oxidative Process for Wastewater Purification, 12 Mar 2010 16:45:17 GMTdjleong@hawaii.edu Grating Sagnac Fourier Transform Spectrometer, 12 Mar 2010 16:45:16 GMTdjleong@hawaii.edu Solid-State/Electrochemical Photoelectrode for Hydrogen Production, 12 Mar 2010 16:45:12 GMTdjleong@hawaii.edu of a New Microtubule-Stabilizing Agent Named Taccalonolide A, 12 Mar 2010 16:45:03 GMTdjleong@hawaii.edu Engineered Banana with Resistance to Banana Bunchy Top Virus, 07 Jan 2010 17:43:53 GMTdjleong@hawaii.edu