Search Results - leng+chee+chang

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A series of new products isolated from a medicinal plant, Vernonia cinerea, controlled human cancer growth by blocking the abnormal functions of the transcription factor, STAT3 signaling. The natural product molecules showed inhibitory effects against growth of triple negative breast cancer which are non-responsive to current hormone therapies and have...

Published: 11/22/2021 | Inventor(s): Leng Chee Chang, James Turkson, Supakit Wongwiwatthananukit, Ui Joung Youn, Dianqing Sun

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Category(s): Healthcare

Natural product inhibitors of Stat3 and NF-kappaB

Physalis peruviana and poha berry fruit have been found to control human cancer growth by blocking the abnormal functions of Stat3 and NF-kappaB signaling pathways. Inhibitory effects were observed in human glioma, bladder carcinoma, and breast cancer cells in vitro. ApplicationsGrowth inhibition in cancers with activated Stat3 and NF-kappaB signaling...

Published: 6/27/2018 | Inventor(s): Leng Chee Chang, John Pezzuto, James Turkson, Mayuramas Sang-Ngern

Keywords(s):

Category(s): Healthcare, Therapeutic