Search Results - Healthcare

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Titanocene-Gold Derivatives as Chemotherapeutics for Renal Cancer
Gold complexes have shown promise in cancer chemotherapy, with several compounds having overcome cisplatin resistance of specific cancer cells, furthering their appeal. Early-transition metal complexes, particularly titanocene-based complexes, are another class of compounds being explored for cancer chemotherapy. Recently novel metallodrugs have be...
Published: 7/20/2018   |   Inventor(s): Joe Ramos, Maria Contel, Jacob Fernandez-Gallardo, Benelita Elie
Category(s): Healthcare
Smart Actuator for Medical Device Locating and Positioning
The invention involves the use of advanced materials and actuators to assist in the positioning of medical devices inserted using transcatheter approaches. The actuator device utilizes shape memory components that are able to achieve movements in multiple directions and resume their original shape in response to selective actuation. Attachment of t...
Published: 9/25/2017   |   Inventor(s): Bardia Konh
Category(s): Devices, Engineering, Healthcare, Materials Science
Plants Expressing the Miraculin Protein, a Sweetener
Researchers at UH-Hilo have developed a method for expressing miraculin, a flavor-altering protein, in lettuce. The protein is found naturally in berries of the miracle berry plant, Synsepalum dulcificum, and binds to sweet receptors on the tongue, temporarily producing a sweet taste for sour foods. The genetically engineered lettuce accumulates f...
Published: 7/26/2017   |   Inventor(s): Michael Shintaku, Lukas Kambic
Keywords(s): Agriculture:Transgenics, Healthcare
Category(s): Agriculture/Aquaculture, Healthcare
Distinguish Zika Virus from Other Flaviviruses Via Simple Serodiagnostic Assays
The recent emergence of Zika virus (ZIKV) and associated microcephaly has created an urgent need for a sensitive, specific, and rapid serodiagnostic test. ZIKV belongs to the genus Flavivirus, which includes several mosquito-borne human pathogens such as dengue virus (DENV) and West Nile virus (WNV). Due to the considerable immune response it eli...
Published: 7/20/2017   |   Inventor(s): Wei-Kung Wang, Wen-Yang Tsai
Category(s): Diagnostic, Healthcare
Selective Inhibitors of GSK3-beta
Technology Glycogen synthase kinase 3 (GSK3) is a ubiquitously expressed serine/threonine kinase that is being investigated clinically for a variety of therapeutic applications including CNS disorders, metabolic disorders and in dental health. Centrally, GSK3 is primarily responsible for aberrant phosphorylation of tau leading to pathologic...
Published: 1/31/2017   |   Inventor(s): Qing Xiao Li, Zhibin Liang
Keywords(s): Healthcare:Alzheimer’s Disease, Healthcare:Metabolic Diseases, Healthcare:Neurological Disorders, Healthcare:Oncology, Healthcare:Therapeutic, Therapeutic
Category(s): Chemistry, Healthcare, Therapeutic
C-Glycosylflavones for prevention and treatment of Alzheimer's disease
The available technology is a method of combating the most common brain disorder worldwide--Alzheimer’s disease. The technology is an extract of corn silk, a product that little research to date has been conducted on. More specifically, this specific corn silk extract containing C-glycosylflavones inhibits a specific kinase attributing to Alz...
Published: 5/13/2016   |   Inventor(s): Qing Xiao Li, Zhibin Liang
Category(s): Healthcare, Biology, Therapeutic
Real-Time Isothermal Sequence Specific Detection of DNA with Non-Contact Temperature Controller (Exclusively Licensed - please inquire to learn more)
Simple, rapid, and specific DNA-based diagnostics tools are urgently needed for variety of clinical health application and critical pathogens detection programs for containment, treatment, and eradication. Unfortunately, most instruments for DNA analysis are bulky, slow, require trained operators applying a sequence of operations for sample prepara...
Published: 2/12/2016   |   Inventor(s): Ryo Kubota, Daniel Jenkins
Category(s): Biology, Genetics/Genomics, Healthcare
Method and Device for Biochemical Sensing (Exclusively Licensed - please inquire for further details)
Medical diagnostics using chemical sensing of antibody, antigens, DNA fragments and other biochemicals are addressed using semiconductor sensors and supportive biochemical processes. This successful marriage of semiconductor sensors and biochemistry address a diversity of potential biochemical diagnostics and measurements including detection an...
Published: 2/11/2016   |   Inventor(s): James Holm-Kennedy
Category(s): Microbiology, Engineering, Biology, Chemistry, Sensors, Healthcare
Method for Reducing or Preventing Immunogenic Response
This invention involves the use of humanized cobra venom factor (hCVF) to prevent or reduce immunogenicity and other unwanted immunological reactions as a consequence of administering biologics therapy. In many therapeutic situations, biologics agents may induce unwanted immune response that can cause clinical challenges and ineffective treatment. ...
Published: 6/16/2015   |   Inventor(s): Carl-Wilhelm Vogel, Paul Finnegan, Julie Rayes, Sebastien Lacroix-Desmazes
Category(s): Healthcare
anti-HMGB1 antibody for mesothelioma
In the US, asbestos causes approximately 2,000 - 3,000 malignant mesothelioma deaths per year, and it contributes to an even larger number of lung carcinomas. The latency from time of exposure to tumor development potentially allows time for intervention to block the mechanism(s) that trigger asbestos-induced carcinogenesis. This invention proposes...
Published: 5/29/2015   |   Inventor(s): Haining Yang, Michele Carbone, Marco Bianchi
Category(s): Healthcare, Therapeutic
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